SCHEMBL18154536

SCHEMBL18154536

CN(C)C(=O)Nc1ccc(OP(=O)(Oc2ccccc2)Oc2ccc(NC(=O)N(C)C)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 8/20 0.50
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TSHR P16473 1/20 0.50
PGR P06401 1/20 0.50
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
THRB P10828 1/20 0.49
GFER P55789 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18154532 0.94 TSHR (0.56) TSHR
SCHEMBL28577858 0.87 TDP1 (0.54) NPY5RHPGDSMN1; SMN2TSHRPGR
SCHEMBL21218592 0.87 TSHR (0.49) NPY5RHPGDSMN1; SMN2TSHRPGR
SCHEMBL18154606 0.82 TP53 (0.52) NPY5RSMN1; SMN2KDM4EALDH1A1KMT2A
SCHEMBL18154535 0.80 TSHR (0.54) TSHRMEN1KMT2A
Fenuron SCHEMBL8366971 0.78 TSHR (0.64) TSHRMEN1KMT2A
Fenuron SCHEMBL9451054 0.78 TSHR (0.64) TSHRMEN1KMT2A
Fenuron SCHEMBL10806698 0.78 TSHR (0.64) TSHRMEN1KMT2A
Fenuron SCHEMBL62004 0.78 TSHR (0.64) TSHRMEN1KMT2A
SCHEMBL687878 0.76 TSHR (0.79) TSHRMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283495-B1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) ALZCHEM TROSTBERG GMBH (DE) 2020-08-26 EP disclosed
EP-3283494-B1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2019-08-07 EP disclosed
EP-3283495-A1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) AlzChem AG (DE) 2018-02-21 EP disclosed
EP-3283494-A1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS AlzChem AG (DE) 2018-02-21 EP disclosed
WO-2016166229-A1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) ALZCHEM AG (DE) 2016-10-20 WO disclosed
WO-2016166226-A1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS ALZCHEM AG (DE) 2016-10-20 WO disclosed