SCHEMBL18154535

SCHEMBL18154535

CN(C)C(=O)Nc1ccc(OP(=S)(Oc2ccc(NC(=O)N(C)C)cc2)Oc2ccc(NC(=O)N(C)C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
APEX1 P27695 1/20 0.46
ROCK2 O75116 1/20 0.46
ROCK1 Q13464 1/20 0.46
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18154532 0.85 TSHR (0.56) TSHRCA12CA1CA2CA9
SCHEMBL18154533 0.83 SMN1; SMN2 (0.55) TSHRMEN1KMT2A
SCHEMBL11297176 0.81 KMT2A (0.67) TSHRCA12CA1CA2CA9
SCHEMBL687878 0.80 TSHR (0.79) TSHRCA12CA1CA2CA9
SCHEMBL18154536 0.80 NPY5R (0.50) TSHRMEN1KMT2A
SCHEMBL7088596 0.79 NPC1 (0.66) TSHR
SCHEMBL28577858 0.78 TDP1 (0.54) TSHRCA12CA1CA2CA9
SCHEMBL21218592 0.78 TSHR (0.49) TSHR
SCHEMBL18193458 0.77 TSHR (0.59) TSHRCA12CA1CA2CA9
SCHEMBL8538067 0.76 NPC1 (0.61) TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428915-B Curing agent and curing accelerator (II) having flame retardant effect for curing epoxy resin 澳泽化学特罗斯特贝格有限公司 2021-02-09 CN disclosed
EP-3283495-B1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) ALZCHEM TROSTBERG GMBH (DE) 2020-08-26 EP disclosed
EP-3283494-B1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2019-08-07 EP disclosed
EP-3283495-A1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) AlzChem AG (DE) 2018-02-21 EP disclosed
EP-3283494-A1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS AlzChem AG (DE) 2018-02-21 EP disclosed
WO-2016166226-A1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS ALZCHEM AG (DE) 2016-10-20 WO disclosed
WO-2016166229-A1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) ALZCHEM AG (DE) 2016-10-20 WO disclosed