SCHEMBL18155004

SCHEMBL18155004

CCC/C(C(=O)O)=C(\OCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
FFAR3 O14843 2/20 0.39
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
THRB P10828 1/20 0.35
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
PGGT1B P53609 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18155006 1.00 ALDH1A1 (0.39) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL30174535 0.91 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL9739502 0.82 SOAT1 (0.44) ALDH1A1FFAR3LMNAHSD17B10ALOX15
SCHEMBL9739514 0.82 SOAT1 (0.44) ALDH1A1FFAR3LMNAHSD17B10ALOX15
SCHEMBL10601454 0.82 SOAT1 (0.44) ALDH1A1FFAR3LMNAHSD17B10ALOX15
SCHEMBL7174086 0.80 ALDH1A1 (0.40) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL7174082 0.78 ALDH1A1 (0.39) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL11658288 0.78 ALDH1A1 (0.53) ALDH1A1FFAR3LMNAHSD17B10ALOX15
SCHEMBL3742164 0.77 ALDH1A1 (0.37) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL184432 0.75 HDAC3 (0.56) ALDH1A1FFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283295-B1 METHOD FOR PREPARING SILICONE-TREATED FILMS OF POLYETHYLENE TEREPHTHALATE (PET) SILICONATURE S P A (IT) 2019-11-20 EP disclosed
US-20180118973-A1 METHOD FOR PREPARING SILICONE-TREATED FILMS OF POLYETHYLENE TEREPHTHALATE (PET) SILICONATURE S.P.A. (IT) 2018-05-03 US disclosed
EP-3283295-A1 METHOD FOR PREPARING SILICONE-TREATED FILMS OF POLYETHYLENE TEREPHTHALATE (PET) Siliconature S.p.A. (IT) 2018-02-21 EP disclosed
WO-2016165796-A1 METHOD FOR PREPARING SILICONE-TREATED FILMS OF POLYETHYLENE TEREPHTHALATE (PET) SILICONATURE S.P.A. (IT) 2016-10-20 WO disclosed