Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760694 | 0.79 | KDM4E (0.56) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL1436159 | 0.75 | KDM4E (0.52) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7866805 | 0.75 | KDM4E (0.52) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL549420 | 0.73 | KDM4E (0.54) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29134994 | 0.72 | KDM4E (0.54) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL750649 | 0.72 | KDM4E (0.58) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL27445624 | 0.72 | KDM4E (0.58) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28677921 | 0.72 | KDM4E (0.54) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL1446966 | 0.72 | MEN1 (0.57) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29478348 | 0.72 | TSHR (0.62) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562920-B2 | Ln(III) and Ga(III) metallacrown complexes | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-02-18 | — | — | US | disclosed |
| US-20180127438-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | NATIONAL SCIENCE FOUNDATION | 2018-05-10 | — | — | US | disclosed |
| EP-3283497-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | The Regents of The University of Michigan (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016166380-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127438-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | NEU3, GALNT3, LGALS3 | TSHR 698/4885KDM4E 4066/4885HPGD 1340/4885 |
| US-10562920-B2 | Ln(III) and Ga(III) metallacrown complexes | NEU3, GALNT3, LGALS3 | TSHR 698/4885KDM4E 4066/4885HPGD 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.