Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527861 | 0.84 | MCL1 (0.66) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL10431295 | 0.84 | PTPN7 (0.53) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL6838793 | 0.84 | MCL1 (0.66) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL31415218 | 0.84 | PTPN7 (0.53) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL4299281 | 0.82 | THRB (0.43) | PTPN7ALOX15TSHRHSD17B10LMNA | |
| SCHEMBL12238280 | 0.81 | PPARD (0.61) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL12238283 | 0.81 | PTGDR2 (0.51) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL20982578 | 0.80 | FFAR4 (0.48) | TSHRL3MBTL1FFAR1 | |
| SCHEMBL2331112 | 0.80 | PTGDR2 (0.50) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL2326829 | 0.80 | PPARD (0.59) | PTPN7ALOX15TSHRHSD17B10MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735402-B | Deksaporin-phospholipid conjugate and preparation method thereof | 大学健康网络 | 2021-03-26 | — | — | CN | disclosed |
| EP-3283493-B1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | UNIV HEALTH NETWORK UHN (CA) | 2020-11-18 | — | — | EP | disclosed |
| EP-3283493-B1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | UNIV HEALTH NETWORK UHN (CA) | 2020-11-18 | — | — | EP | disclosed |
| US-10729792-B2 | Texaphyrin-phospholipid conjugates and methods of preparing same | UNIVERSITY HEALTH NETWORK (CA) | 2020-08-04 | — | — | US | disclosed |
| US-10729792-B2 | Texaphyrin-phospholipid conjugates and methods of preparing same | UNIVERSITY HEALTH NETWORK (CA) | 2020-08-04 | — | — | US | disclosed |
| US-9975878-B2 | Substituted triazine BMI-1 inhibitors | PTC THERAPEUTICS, INC. (US) | 2018-05-22 | — | — | US | disclosed |
| US-20180104364-A1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | UNIVERSITY HEALTH NETWORK (CA) | 2018-04-19 | — | — | US | disclosed |
| US-20180104364-A1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | UNIVERSITY HEALTH NETWORK (CA) | 2018-04-19 | — | — | US | disclosed |
| US-20180104364-A1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | UNIVERSITY HEALTH NETWORK (CA) | 2018-04-19 | — | — | US | disclosed |
| CN-107735402-A | Texaphyrin phospholipid conjugates and preparation method thereof | 大学健康网络 | 2018-02-23 | — | — | CN | disclosed |
| EP-3283493-A1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | University Health Network (UHN) (CA) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016165006-A1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | UNIVERSITY HEALTH NETWORK (CA) | 2016-10-20 | — | — | WO | disclosed |
| WO-2016165006-A1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | UNIVERSITY HEALTH NETWORK (CA) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104364-A1 | TEXAPHYRIN-PHOSPHOLIPID CONJUGATES AND METHODS OF PREPARING SAME | PLTP, PHOSPHO1, TEX13A | PTPN7 2282/4885ALOX15 1219/4885TSHR 1916/4885 |
| US-10729792-B2 | Texaphyrin-phospholipid conjugates and methods of preparing same | PLTP, PHOSPHO1, TEX13A | PTPN7 2282/4885ALOX15 1219/4885TSHR 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.