Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825954 | 0.90 | CRBN (0.37) | CRBNSMN1; SMN2TDP1 | |
| SCHEMBL10046305 | 0.80 | CRBN (0.39) | CRBNSMN1; SMN2TDP1 | |
| SCHEMBL825880 | 0.79 | CRBN (0.38) | CRBNSMN1; SMN2TDP1 | |
| SCHEMBL825863 | 0.78 | CRBN (0.39) | CRBNSMN1; SMN2TDP1 | |
| SCHEMBL14402369 | 0.78 | CRBN (0.39) | CRBNSMN1; SMN2TDP1 | |
| SCHEMBL825941 | 0.77 | CRBN (0.37) | CRBNSMN1; SMN2TDP1 | |
| SCHEMBL825885 | 0.74 | LMNA (0.39) | CRBN | |
| SCHEMBL825892 | 0.73 | CRBN (0.40) | CRBNSMN1; SMN2 | |
| SCHEMBL18155543 | 0.70 | ALDH1A1 (0.37) | CRBNSMN1; SMN2TDP1 | |
| SCHEMBL825882 | 0.68 | CRBN (0.38) | CRBNSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004614-B1 | TETRAHALOGENATED COMPOUNDS USEFUL AS INHIBITORS OF ANGIOGENESIS | US GOV HEALTH & HUMAN SERV (US) | 2016-10-19 | — | — | EP | disclosed |