Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24473563 | 1.00 | ACLY (0.35) | ACLYSOAT1GMNNUSP2CYP1A2 | |
| SCHEMBL18155568 | 0.95 | ACLY (0.43) | ACLYSOAT1GMNNUSP2CYP1A2 | |
| SCHEMBL17131053 | 0.90 | ACLY (0.42) | ACLY | |
| SCHEMBL24473356 | 0.86 | ACLY (0.37) | ACLYGMNNUSP2CYP1A2POLB | |
| SCHEMBL24473586 | 0.86 | ACLY (0.37) | ACLYGMNNUSP2CYP1A2POLB | |
| SCHEMBL24473590 | 0.82 | TRPV1 (0.38) | ACLY | |
| SCHEMBL24473591 | 0.82 | ACLY (0.37) | ACLY | |
| SCHEMBL13282208 | 0.79 | ALDH1A1 (0.39) | USP2CYP3A4RECQL | |
| SCHEMBL13282112 | 0.79 | ALDH1A1 (0.39) | USP2CYP3A4RECQL | |
| SCHEMBL19289866 | 0.79 | ALDH1A1 (0.39) | USP2CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159352-A1 | STITCHED POLYPEPTIDES | President and Fellows of Harvard College (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2508531-B1 | Stitched polypeptides | HARVARD COLLEGE (US) | 2016-10-19 | — | — | EP | disclosed |