Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13954202 | 0.86 | DPP4 (0.51) | DPP4HTR1AHTR7ACE | |
| SCHEMBL14421631 | 0.80 | POLB (0.39) | DPP4SPHK1 | |
| SCHEMBL19658296 | 0.79 | ACE (0.44) | SPHK1ACE | |
| SCHEMBL3891727 | 0.78 | DPP4 (0.55) | DPP4SPHK1HTR1AHTR7ACE | |
| SCHEMBL14417627 | 0.77 | RAB9A (0.49) | — | |
| SCHEMBL10884099 | 0.77 | DPP4 (0.54) | DPP4HTR1AHTR7ACE | |
| SCHEMBL1493753 | 0.76 | DPP4 (0.47) | DPP4HTR1AHTR7ACE | |
| SCHEMBL7710658 | 0.76 | DPP4 (0.45) | DPP4SPHK1HTR1AHTR7ACE | |
| SCHEMBL21100049 | 0.75 | ACE (0.41) | SPHK1ACE | |
| SCHEMBL14463150 | 0.75 | DPP4 (0.51) | DPP4HTR1AHTR7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2901160-B1 | METHOD FOR SPECIFICALLY DETECTING A MATRIX METALLOPROTEINASE (MMP) WHICH IS ONLY OF INTEREST IN THE ACTIVE FORM THEREOF, IN A SAMPLE | COMMISSARIAT À L EN ATOMIQUE ET AUX EN ALTERNATIVES (FR) | 2016-10-19 | — | — | EP | disclosed |