Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.45 |
| ▸ | HTR1A | P08908 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 6/20 | 0.42 |
| ▸ | MVD | P53602 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421615 | 0.84 | MVD (0.41) | DPP4HTR1AHTR7MVDSPHK1 | |
| SCHEMBL6830137 | 0.80 | POLB (0.42) | DPP4MVD | |
| SCHEMBL6786825 | 0.79 | MVD (0.57) | MVDACE | |
| SCHEMBL8097341 | 0.79 | MVD (0.57) | MVDACE | |
| SCHEMBL6831054 | 0.78 | POLB (0.45) | DPP4HTR1A | |
| SCHEMBL6827882 | 0.78 | POLB (0.45) | DPP4HTR1A | |
| SCHEMBL6830216 | 0.78 | POLB (0.45) | DPP4HTR1A | |
| SCHEMBL6830930 | 0.76 | POLB (0.41) | DPP4OPRM1 | |
| SCHEMBL28397270 | 0.76 | MVD (0.43) | DPP4MVDSPHK1ACE | |
| SCHEMBL18155883 | 0.76 | DPP4 (0.44) | DPP4HTR1AHTR7SPHK1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263730-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | Applied Research Systems ARS Holding N.V. (AN) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001060798-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-08-23 | — | — | WO | disclosed |