SCHEMBL18156545

SCHEMBL18156545

CC(F)(c1cc(I)c(NC(=O)c2cccc(NC(=O)c3cccnc3Cl)c2)c(C(F)(F)F)c1)C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PTGES O14684 1/20 0.45
KCNK3 O14649 2/20 0.43
KCNK9 Q9NPC2 2/20 0.43
RXFP1 Q9HBX9 5/20 0.43
ALDH1A1 P00352 1/20 0.43
CSF1R P07333 2/20 0.43
CES1 P23141 1/20 0.42
BRAF P15056 3/20 0.41
RHOC P08134 1/20 0.41
RHOA P61586 1/20 0.41
GRM4 Q14833 1/20 0.41
PPARG P37231 2/20 0.40
PPARD Q03181 2/20 0.40
NR1H4 Q96RI1 2/20 0.40
PPARA Q07869 1/20 0.40
RAF1 P04049 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427414 0.91 MEN1 (0.51) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1766845 0.91 MEN1 (0.51) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1766530 0.89 MEN1 (0.48) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1767168 0.85 MEN1 (0.55) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1766529 0.83 MEN1 (0.53) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1766281 0.82 KMT2A (0.53) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL19518121 0.82 MEN1 (0.53) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1766865 0.81 PTGES (0.49) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1766654 0.81 MEN1 (0.51) MEN1KMT2APTGESKCNK3KCNK9
SCHEMBL1824465 0.79 KMT2A (0.55) MEN1KMT2APTGESKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081552-A1 PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2016-10-19 EP disclosed