Sugi Predict

Sugi Predict / Compounds / SCHEMBL1766845

SCHEMBL1766845

SCHEMBL1766845

O=C(Nc1c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C(F)(F)F)c1cccc(NC(=O)c2cccnc2Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ PTGES O14684 1/20 0.49
▸ RXFP1 Q9HBX9 6/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ KCNK3 O14649 2/20 0.44
▸ KCNK9 Q9NPC2 2/20 0.44
▸ CSF1R P07333 1/20 0.44
▸ CES1 P23141 1/20 0.43
▸ RHOC P08134 1/20 0.42
▸ RHOA P61586 1/20 0.42
▸ GRM4 Q14833 1/20 0.42
▸ PPARG P37231 2/20 0.41
▸ PPARD Q03181 2/20 0.41
▸ NR1H4 Q96RI1 2/20 0.41
▸ PPARA Q07869 1/20 0.41
▸ MAPT P10636 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ EPHX2 P34913 1/20 0.41
▸ MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427414 1.00 MEN1 (0.51) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL1766530 0.96 MEN1 (0.48) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL1767168 0.94 MEN1 (0.55) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL1766529 0.92 MEN1 (0.53) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL18156545 0.91 MEN1 (0.49) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL1766654 0.90 MEN1 (0.51) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL1766865 0.90 PTGES (0.49) MEN1KMT2APTGESRXFP1KCNK3
SCHEMBL1766281 0.89 KMT2A (0.53) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL19518121 0.88 MEN1 (0.53) MEN1KMT2APTGESRXFP1ALDH1A1
SCHEMBL1766340 0.87 RXFP1 (0.53) MEN1KMT2APTGESRXFP1KCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 — — EP claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 — — CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 — — US claimed
CN-108289456-B Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2022-01-11 — — CN claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 — — EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 — — US claimed
CN-113367135-A Agricultural mixtures comprising carboxamide compounds 巴斯夫农业化学品有限公司 2021-09-10 — — CN claimed
CN-113303339-A Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2021-08-27 — — CN claimed
EP-3057420-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
EP-3057418-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products, B.V. (NL) 2016-08-24 — — EP claimed
WO-2016128261-A2 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2016-08-18 — — WO claimed
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
WO-2016079043-A1 PESTICIDAL COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2016-05-26 — — WO claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed
WO-2015055752-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055755-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055757-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF SE (DE) 2015-04-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH MEN1 1988/4885KMT2A 2611/4885PTGES 3570/4885
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND NAAA, AADAC, PYCARD MEN1 991/4885KMT2A 855/4885PTGES 4584/4885
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound ATP5ME, MT-ATP6, ATP5MG MEN1 1305/4885KMT2A 2059/4885PTGES 2707/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 MEN1 157/4885KMT2A 2080/4885PTGES 1400/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT MEN1 1895/4885KMT2A 3738/4885PTGES 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.