SCHEMBL18156632

SCHEMBL18156632

CCCc1ccc(-c2cc(F)c(C(F)(F)Br)c(F)c2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.40
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
RARB P10826 2/20 0.36
CHKA P35790 1/20 0.35
ALOX5 P09917 1/20 0.34
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
RARA P10276 1/20 0.31
RARG P13631 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1814580 0.91 RARB (0.40) PDK2RARBCHKANPC1TP53
SCHEMBL17407514 0.91 RARB (0.43) RARBCHKANPC1RAB9ASMN1; SMN2
SCHEMBL12199003 0.90 RARB (0.48) RARBTP53HSD17B10RARARARG
SCHEMBL13002328 0.89 PDK2 (0.40) PDK2CNR1CNR2RARBCHKA
SCHEMBL13002234 0.87 ALOX5 (0.39) PDK2CNR1CNR2RARBCHKA
SCHEMBL12198989 0.86 RARB (0.40) RARBCHKANPC1RAB9ASMN1; SMN2
SCHEMBL15744304 0.84 PDK2 (0.37) PDK2CNR1CNR2RARBALOX5
SCHEMBL13002338 0.84 RARB (0.40) PDK2CNR1CNR2RARBCHKA
SCHEMBL13002235 0.84 PDK2 (0.37) PDK2CNR1CNR2RARBCHKA
SCHEMBL16562701 0.83 RARB (0.41) RARBCHKANPC1TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9783735-B2 Liquid crystal display device and liquid crystal composition used therefor SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-10 US disclosed
US-9783735-B2 Liquid crystal display device and liquid crystal composition used therefor SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-10 US disclosed
EP-3222696-A2 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR Samsung Display Co., Ltd. (KR) 2017-09-27 EP disclosed
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR DONGJIN SEMICHEM CO., LTD. (KR) 2016-10-20 US disclosed
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR DONGJIN SEMICHEM CO., LTD. (KR) 2016-10-20 US disclosed
EP-3081621-A2 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR Samsung Display Co., Ltd. (KR) 2016-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR SLC39A11, CYP4F11, WEE1 PDK2 1599/4885CNR1 1118/4885CNR2 1784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.