Sugi Predict

Sugi Predict / Compounds / SCHEMBL18157080

SCHEMBL18157080

SCHEMBL18157080

c1cc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)cc(-c2cccc(-c3cccc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)c3)n2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ ATM Q13315 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ KMT2A Q03164 4/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ GAA P10253 1/20 0.37
▸ PDE10A Q9Y233 1/20 0.36
▸ HTR1A P08908 1/20 0.35
▸ HTR7 P34969 1/20 0.35
▸ IL1R1 P14778 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ HTT P42858 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ GRM5 P41594 1/20 0.34
▸ RXFP1 Q9HBX9 1/20 0.33
▸ TUBB4A P04350 1/20 0.33
▸ TUBB P07437 1/20 0.33
▸ TUBA3C P0DPH7 1/20 0.33
▸ TUBA1B P68363 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23204635 0.98 L3MBTL1 (0.47) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL8400384 0.97 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL29353726 0.97 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL29446477 0.97 L3MBTL1 (0.52) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL16674304 0.95 L3MBTL1 (0.50) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL4400328 0.95 L3MBTL1 (0.50) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL15867543 0.94 L3MBTL1 (0.53) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL16089834 0.93 L3MBTL1 (0.42) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL16089814 0.93 L3MBTL1 (0.42) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL13203207 0.92 L3MBTL1 (0.47) L3MBTL1ATMKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10305044-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-05-28 — — US disclosed
US-20160308139-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-20 — — US disclosed
US-20160308139-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10305044-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CYP1A1, NR2E3 L3MBTL1 522/4885ATM 4087/4885KDM4E 2956/4885
US-20160308139-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CRY1, CYP1A1, NR2E3 L3MBTL1 522/4885ATM 4087/4885KDM4E 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.