Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160332 | 0.95 | KDM4E (0.39) | PLK4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18157756 | 0.90 | KMT2A (0.52) | PLK4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18157765 | 0.84 | ALK (0.50) | PLK4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18157747 | 0.84 | ALK (0.50) | PLK4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18157780 | 0.77 | PADI4 (0.41) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL18160331 | 0.76 | MAPT (0.47) | PLK4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18157762 | 0.73 | ALK (0.50) | PLK4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18160337 | 0.72 | NPC1 (0.34) | PLK4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18157753 | 0.72 | PADI4 (0.43) | KMT2AMEN1NPC1RAB9APADI4 | |
| SCHEMBL710442 | 0.71 | NPC1 (0.58) | KMT2AMEN1NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | PLK4 1462/4885KMT2A 2258/4885MEN1 1398/4885 |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | PLK4 1462/4885KMT2A 2258/4885MEN1 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.