SCHEMBL18157956

SCHEMBL18157956

CN(C)CCNC(Cc1ccccn1)c1ccccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 7/20 0.47
SLC6A2 P23975 6/20 0.47
SLC6A4 P31645 6/20 0.47
SCN1A P35498 3/20 0.47
SCN2A Q99250 3/20 0.47
SCN3A Q9NY46 3/20 0.47
CYP2C19 P33261 4/20 0.47
TSHR P16473 3/20 0.45
KCNH2 Q12809 6/20 0.42
HRH3 Q9Y5N1 6/20 0.42
CHRM1 P11229 5/20 0.42
HRH1 P35367 5/20 0.42
SLC6A3 Q01959 5/20 0.42
ADRA2B P18089 4/20 0.42
HTR2A P28223 3/20 0.42
CHRM5 P08912 3/20 0.42
CYP2D6 P10635 3/20 0.42
LMNA P02545 3/20 0.42
NFKB1 P19838 2/20 0.42
THPO P40225 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18158098 0.92 CHRM2 (0.43) CHRM2SLC6A2SLC6A4SCN1ASCN2A
SCHEMBL18157959 0.82 HRH3 (0.51) CYP2C19HRH3HRH1CYP2D6LMNA
SCHEMBL58388 0.81 HRH1 (0.46) CHRM2CYP2C19TSHRHRH3HRH1
SCHEMBL18157958 0.81 FDPS (0.43) CHRM2CYP2C19TSHRHRH3CYP2D6
SCHEMBL18158015 0.81 SCN8A (0.41) CYP2C19HRH3LMNAKCNA5ALDH1A1
SCHEMBL18157952 0.81 FDPS (0.40) CHRM2CYP2C19TSHRKCNH2HRH3
SCHEMBL18157961 0.78 TLR7 (0.40) CYP2C19KCNH2HRH3LMNASMN1; SMN2
SCHEMBL18158011 0.78 FDPS (0.41) CYP2C19TSHRHRH3CYP2D6LMNA
SCHEMBL20661521 0.77 CYP2C19 (0.46) CHRM2SLC6A2SLC6A4SCN1ASCN2A
SCHEMBL18158080 0.77 CHRM2 (0.43) CHRM2CYP2C19HRH3HRH1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 CHRM2 1881/4885SLC6A2 2951/4885SLC6A4 2309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.