SCHEMBL18158357

SCHEMBL18158357

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5cccc(-c6nc(-c7ccccc7)c7sc8ccccc8c7n6)c5)c4)c3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.38
▸ LMNA P02545 3/20 0.38
▸ MAPT P10636 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ LIMK1 P53667 4/20 0.34
▸ PIM1 P11309 2/20 0.33
▸ PIM2 Q9P1W9 2/20 0.33
▸ PIM3 Q86V86 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ CYP19A1 P11511 1/20 0.33
▸ TNKS O95271 2/20 0.33
▸ TNKS2 Q9H2K2 2/20 0.33
▸ KRAS P01116 1/20 0.33
▸ ADORA2A P29274 1/20 0.32
▸ ADORA1 P30542 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18158342 1.00 MEN1 (0.38) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL18158344 1.00 MEN1 (0.38) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL18158356 0.99 MEN1 (0.39) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL16581202 0.98 LIMK1 (0.37) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL18158369 0.95 MEN1 (0.36) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL18158372 0.95 MEN1 (0.36) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL18158362 0.95 MEN1 (0.36) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL18158376 0.94 MEN1 (0.36) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL16581216 0.94 CYP1A1 (0.38) MEN1LMNAMAPTKMT2AKDM4E
SCHEMBL18158352 0.93 MEN1 (0.43) MEN1LMNAMAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10600971-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2020-03-24 — — US disclosed
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2019-06-11 — — US disclosed
US-20180047916-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-02-15 — — US disclosed
US-20180047916-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-02-15 — — US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 — — US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 — — US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 — — US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 — — US disclosed
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 — — US disclosed
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MEN1 838/4885LMNA 1491/4885MAPT 1162/4885
US-10600971-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 MEN1 2872/4885LMNA 4755/4885MAPT 2701/4885
US-20180047916-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 MEN1 2872/4885LMNA 4755/4885MAPT 2701/4885
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device OR10J3, OR51E2, OXER1 MEN1 2391/4885LMNA 4820/4885MAPT 2759/4885
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE OCIAD2, OCIAD1, OR10J3 MEN1 2593/4885LMNA 4816/4885MAPT 2190/4885
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 MEN1 2498/4885LMNA 4821/4885MAPT 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback