SCHEMBL18158379

SCHEMBL18158379

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc(-c5nc(-c6ccccc6)c6sc7ccccc7c6n5)cc4)c3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ ATM Q13315 1/20 0.42
▸ LIMK1 P53667 5/20 0.40
▸ PIM1 P11309 2/20 0.38
▸ PIM2 Q9P1W9 2/20 0.38
▸ PIM3 Q86V86 1/20 0.38
▸ TNKS O95271 3/20 0.38
▸ TNKS2 Q9H2K2 3/20 0.38
▸ PIK3CA P42336 1/20 0.37
▸ PI4KA P42356 1/20 0.37
▸ PI4KB Q9UBF8 1/20 0.37
▸ WHR1 P49842 1/20 0.36
▸ LIMK2 P53671 1/20 0.35
▸ ADORA2A P29274 1/20 0.35
▸ ADORA1 P30542 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18158380 1.00 MEN1 (0.42) MEN1KMT2AATMLIMK1PIM1
SCHEMBL18158378 1.00 MEN1 (0.42) MEN1KMT2AATMLIMK1PIM1
SCHEMBL19797729 1.00 MEN1 (0.42) MEN1KMT2AATMLIMK1PIM1
SCHEMBL19497506 1.00 MEN1 (0.42) MEN1KMT2AATMLIMK1PIM1
SCHEMBL19797731 0.99 MEN1 (0.43) MEN1KMT2AATMLIMK1PIM1
SCHEMBL19797710 0.99 MEN1 (0.43) MEN1KMT2AATMLIMK1PIM1
SCHEMBL19797713 0.99 MEN1 (0.43) MEN1KMT2AATMLIMK1PIM1
SCHEMBL19797712 0.99 MEN1 (0.40) MEN1KMT2AATMLIMK1PIM1
SCHEMBL19797714 0.99 MEN1 (0.43) MEN1KMT2AATMLIMK1PIM1
SCHEMBL18018290 0.99 LIMK1 (0.40) MEN1KMT2AATMLIMK1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2019-06-11 — — US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 — — US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 — — US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 — — US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 — — US disclosed
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 — — US disclosed
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MEN1 838/4885KMT2A 2013/4885ATM 1355/4885
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device OR10J3, OR51E2, OXER1 MEN1 2391/4885KMT2A 4764/4885ATM 4359/4885
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE OCIAD2, OCIAD1, OR10J3 MEN1 2593/4885KMT2A 3837/4885ATM 4302/4885
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 MEN1 2498/4885KMT2A 4763/4885ATM 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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