Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 4/20 | 0.58 |
| ▸ | TERT | O14746 | 2/20 | 0.51 |
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24239532 | 1.00 | DTYMK (0.58) | DTYMKTERTTK1F2POLB | |
| SCHEMBL18158887 | 1.00 | DTYMK (0.58) | DTYMKTERTTK1F2POLB | |
| SCHEMBL24239526 | 0.95 | TERT (0.57) | DTYMKTERTTK1F2POLB | |
| SCHEMBL27062508 | 0.93 | DTYMK (0.55) | DTYMKTERTTK1F2POLB | |
| SCHEMBL27062466 | 0.93 | DTYMK (0.60) | DTYMKTERTTK1F2POLB | |
| SCHEMBL5852678 | 0.91 | DTYMK (0.63) | DTYMKTERTTK1 | |
| SCHEMBL22352121 | 0.90 | POLB (0.54) | POLB | |
| SCHEMBL20763160 | 0.90 | POLB (0.54) | POLB | |
| SCHEMBL16410980 | 0.90 | POLB (0.47) | DTYMKPOLB | |
| SCHEMBL16221581 | 0.90 | DTYMK (0.53) | DTYMKTERTTK1F2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017053722-A1 | MODULATORS OF KRAS EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-03-30 | — | — | WO | disclosed |
| WO-2016168592-A2 | COMPOSITIONS FOR MODULATING C9ORF72 EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2016-10-20 | — | — | WO | disclosed |