Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247044 | 0.84 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL6420271 | 0.79 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL25254764 | 0.78 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL4220911 | 0.78 | CXCR2 (0.56) | MAPK1KDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL8806506 | 0.78 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL424411 | 0.77 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL29568623 | 0.77 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 | |
| SCHEMBL796584 | 0.76 | MAPK1 (0.51) | MAPK1KDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL25219858 | 0.76 | ALDH1A1 (0.54) | MAPK1KDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL29651058 | 0.76 | MAPK1 (0.69) | MAPK1KDM4EL3MBTL1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | VIP, MRPL21, THEM6 | MAPK1 688/4885KDM4E 4608/4885L3MBTL1 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.