SCHEMBL18158970

SCHEMBL18158970

COOC(=O)COc1cn([C@@H]2O[C@H](COP3(=O)OP(=O)(O)OP(=O)(O)O3)[C@H](O)C2O)c(=O)[nH]c1=O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 10/20 0.47
P2RY2 P41231 1/20 0.42
PYGM P11217 3/20 0.41
DNPH1 O43598 1/20 0.41
P2RY14 Q15391 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15810837 0.93 P2RY6 (0.48) P2RY6P2RY2PYGMDNPH1P2RY14
SCHEMBL18852610 0.93 P2RY6 (0.48) P2RY6P2RY2PYGMDNPH1P2RY14
SCHEMBL18287234 0.93 P2RY6 (0.48) P2RY6P2RY2PYGMDNPH1P2RY14
SCHEMBL18161337 0.86 PYGM (0.55) P2RY6PYGMDNPH1
SCHEMBL18158974 0.86 PYGM (0.55) P2RY6PYGMDNPH1
SCHEMBL18161328 0.82 P2RY6 (0.56) P2RY6P2RY2DNPH1P2RY14
SCHEMBL18158971 0.82 P2RY6 (0.56) P2RY6P2RY2DNPH1P2RY14
SCHEMBL18161336 0.81 P2RY6 (0.66) P2RY6P2RY2P2RY14
SCHEMBL18158973 0.81 P2RY6 (0.66) P2RY6P2RY2P2RY14
SCHEMBL17210990 0.80 BCHE (0.51) P2RY6P2RY2PYGMDNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 P2RY6 1545/4885P2RY2 2899/4885PYGM 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.