Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17165540 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TDP1TP53CYP1A2CYP3A4 | |
| SCHEMBL17065883 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1TP53CYP1A2CYP3A4 | |
| SCHEMBL17420850 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TDP1TP53CYP1A2CYP3A4 | |
| SCHEMBL17065884 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TDP1TP53CYP1A2CYP3A4 | |
| SCHEMBL17876505 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNAADORA1MAOB | |
| SCHEMBL16801198 | 0.78 | ATM (0.47) | ALDH1A1TDP1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL25244348 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TDP1TP53CYP1A2CYP3A4 | |
| SCHEMBL19651121 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TDP1TP53CYP1A2CYP3A4 | |
| SCHEMBL16801273 | 0.76 | KDM4E (0.45) | ALDH1A1CYP1A2CYP2D6MAPK1LMNA | |
| SCHEMBL18159635 | 0.76 | KDM4E (0.45) | ALDH1A1CYP1A2CYP2D6MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | ALDH1A1 1740/4885TDP1 3230/4885TP53 2919/4885 |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | ALDH1A1 1740/4885TDP1 3230/4885TP53 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.