Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.71 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.71 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.71 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.69 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.69 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.60 |
| ▸ | RRM1 | P23921 | 1/20 | 0.59 |
| ▸ | TLR2 | O60603 | 6/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | NMT2 | O60551 | 2/20 | 0.43 |
| ▸ | NMT1 | P30419 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159955 | 0.99 | GNAI3 (0.70) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL18653407 | 0.94 | GNAI3 (0.60) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL13318345 | 0.94 | GNAI3 (0.60) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL22991807 | 0.93 | GNAI3 (0.80) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL13318350 | 0.92 | GNAI3 (0.62) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL13318347 | 0.92 | SIRT6 (0.60) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL18672578 | 0.92 | GNAI3 (0.61) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL13318346 | 0.92 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL13318352 | 0.92 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SIRT1SIRT6 | |
| SCHEMBL13318351 | 0.92 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SIRT1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603953-B2 | Dendrimer compositions, methods of synthesis, and uses thereof | YANG, Guanghua (FR) | 2017-03-28 | — | — | US | disclosed |
| US-9603953-B2 | Dendrimer compositions, methods of synthesis, and uses thereof | YANG, Guanghua (FR) | 2017-03-28 | — | — | US | disclosed |
| US-20160303261-A1 | DENDRIMER COMPOSITIONS, METHODS OF SYNTHESIS, AND USES THEREOF | SADEG, Nouredine (FR) | 2016-10-20 | — | — | US | disclosed |
| US-20160303261-A1 | DENDRIMER COMPOSITIONS, METHODS OF SYNTHESIS, AND USES THEREOF | SADEG, Nouredine (FR) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303261-A1 | DENDRIMER COMPOSITIONS, METHODS OF SYNTHESIS, AND USES THEREOF | DDOST, CD44, CLTB | GNAI3 871/4885GNAO1 1940/4885GNAI1 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.