Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | CDC25C | P30307 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 10/20 | 0.38 |
| ▸ | CCND1 | P24385 | 10/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 6/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.37 |
| ▸ | CDK2 | P24941 | 6/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 5/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 5/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 5/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 4/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16855803 | 0.87 | PARP1 (0.49) | PARP1CDK4CCND1CDK5CDK5R1 | |
| SCHEMBL15583044 | 0.78 | PARP1 (0.39) | PARP1CDC25ACDC25CGSK3BMEN1 | |
| SCHEMBL25868511 | 0.78 | PARP1 (0.39) | PARP1CDC25ACDC25CGSK3BMEN1 | |
| SCHEMBL13221849 | 0.76 | PARP1 (0.40) | PARP1GSK3BMEN1MAPTKMT2A | |
| SCHEMBL170829 | 0.74 | PARP1 (0.47) | PARP1CDC25ACDC25CCDK4CCND1 | |
| SCHEMBL3947648 | 0.70 | WEE1 (0.43) | PARP1CDK4CCND1CDK5CDK5R1 | |
| SCHEMBL8442002 | 0.70 | PARP1 (0.42) | PARP1CDC25ACDC25CMEN1MAPT | |
| SCHEMBL3946790 | 0.68 | PARP1 (0.37) | PARP1CDK4CCND1GSK3BCDK2 | |
| SCHEMBL2854316 | 0.68 | PARP1 (0.36) | PARP1CDK4CCND1CDK5CDK5R1 | |
| SCHEMBL12031536 | 0.68 | PARP1 (0.42) | PARP1CDK4CCND1CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | PHAX, RNMT, POLM | PARP1 1992/4885CDC25A 2366/4885CDC25C 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.