Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25868511 | 0.98 | PARP1 (0.39) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL15583044 | 0.98 | PARP1 (0.39) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL7601076 | 0.80 | PARP1 (0.50) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL30606639 | 0.80 | PARP1 (0.50) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL29541 | 0.80 | PARP1 (0.50) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL7598089 | 0.80 | PARP1 (0.50) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL18165030 | 0.76 | PARP1 (0.43) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL25872094 | 0.76 | S100A4 (0.32) | PARP1MEN1CYP1A2BLMPMP22 | |
| SCHEMBL7781183 | 0.75 | PARP1 (0.35) | PARP1CASP7NPSR1CYP3A4TDP1 | |
| SCHEMBL278438 | 0.74 | PARP1 (0.59) | PARP1CASP7NPSR1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404705-B2 | Naphthalene amidine imides | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| US-20100202984-A1 | Naphthalene amidine imides | BASF SE (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100202984-A1 | Naphthalene amidine imides | NES, TXN2, NAT1 | PARP1 1069/4885CASP7 2081/4885NPSR1 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.