⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27875972 | 0.98 | — | — | |
| SCHEMBL1097688 | 0.86 | — | — | |
| SCHEMBL4685916 | 0.84 | TBXAS1 (0.75) | — | |
| SCHEMBL28303304 | 0.84 | — | — | |
| SCHEMBL4773938 | 0.84 | TBXAS1 (0.75) | — | |
| SCHEMBL25322190 | 0.82 | TBXAS1 (0.79) | — | |
| SCHEMBL25320746 | 0.82 | TBXAS1 (0.79) | — | |
| SCHEMBL25315015 | 0.82 | TBXAS1 (0.79) | — | |
| SCHEMBL6267092 | 0.82 | TBXAS1 (0.79) | — | |
| SCHEMBL9640710 | 0.82 | TBXAS1 (0.79) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693551-A | Dihydropyrazole azepine compound, pharmaceutical composition containing same and application of compound in resisting tumor | 浙江大学 | 2023-09-05 | — | — | CN | claimed |
| CN-110590708-B | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2021-08-17 | — | — | CN | claimed |
| EP-3862354-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2021-08-11 | — | — | EP | claimed |
| EP-2824105-B1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2021-03-31 | — | — | EP | claimed |
| CN-110590708-A | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2019-12-20 | — | — | CN | claimed |
| US-10421954-B2 | Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same | NEW YORK UNIVERSITY (US) | 2019-09-24 | — | — | US | claimed |
| US-9969773-B2 | Polymers, pharmaceutical compositions and methods of synthesizing the same | NEW YORK UNIVERSITY (US) | 2018-05-15 | — | — | US | claimed |
| CN-108003035-A | A kind of synthetic method of pharmaceutical intermediate 3-Aminotrifluorotoluene | 徐州诺克非医药科技有限公司 | 2018-05-08 | — | — | CN | claimed |
| EP-1175383-B1 | GLUCOCORTICOID RECEPTOR MODULATORS | PFIZER PROD INC (US) | 2018-03-14 | — | — | EP | claimed |
| US-9629830-B2 | EphA4 inhibitors as neuroprotective agents | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-04-25 | — | — | US | claimed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | claimed |
| WO-1992006978-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-30 | — | — | WO | claimed |
| EP-0437508-A4 | NON-PEPTIDE RENIN INHIBITORS | — | 1991-11-06 | — | — | EP | claimed |
| EP-0437508-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1991-07-24 | — | — | EP | claimed |
| EP-0400451-A1 | Benzisothiazolazo dyes with a coupling component of thiazole or pyridine series | BASF Aktiengesellschaft (DE) | 1990-12-05 | — | — | EP | claimed |
| EP-0371467-A2 | Beta-amino boron acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-06 | — | — | EP | claimed |
| WO-1990003971-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-04-19 | — | — | WO | claimed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | claimed |
| EP-0124067-B1 | 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1986-12-17 | — | — | EP | claimed |
| EP-0124067-A1 | 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | claimed |