Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538044 | 0.89 | KDM4E (0.81) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL23225351 | 0.88 | KDM4E (0.77) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL18521980 | 0.86 | KDM4E (0.71) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL19146242 | 0.86 | KDM4E (0.71) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL9703289 | 0.86 | KDM4E (0.74) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL22315215 | 0.86 | KDM4E (0.74) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL16568124 | 0.85 | KDM4E (0.73) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL23157268 | 0.85 | KDM4E (0.73) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL2282380 | 0.85 | KDM4E (0.73) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL30057780 | 0.85 | KDM4E (1.00) | KDM4EPOLA1TAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125854-B1 | OLIGONUCLEOTIDES CONTAINING HIGH CONCENTRATIONS OF GUANINE MONOMERS | KUROS BIOSCIENCES AG (CH) | 2016-10-26 | — | — | EP | disclosed |