Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 13/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 13/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166274 | 0.93 | P2RX3 (0.49) | P2RX3P2RX2FAAH | |
| SCHEMBL18166390 | 0.93 | P2RX3 (0.50) | P2RX3P2RX2FAAH | |
| SCHEMBL18166429 | 0.89 | P2RX3 (0.43) | P2RX3P2RX2 | |
| SCHEMBL18166350 | 0.89 | P2RX3 (0.43) | P2RX3P2RX2 | |
| SCHEMBL18166356 | 0.89 | P2RX3 (0.43) | P2RX3P2RX2 | |
| SCHEMBL10244055 | 0.89 | P2RX3 (0.60) | P2RX3P2RX2 | |
| SCHEMBL18166281 | 0.86 | P2RX3 (0.41) | P2RX3P2RX2FAAH | |
| SCHEMBL18166357 | 0.86 | P2RX3 (0.46) | P2RX3P2RX2FAAH | |
| SCHEMBL18166289 | 0.84 | P2RX3 (0.39) | P2RX3P2RX2 | |
| SCHEMBL18036454 | 0.82 | P2RX3 (0.41) | P2RX3P2RX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |