Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166274 | 0.92 | P2RX3 (0.49) | P2RX3P2RX2FAAH | |
| SCHEMBL18166452 | 0.89 | P2RX3 (0.39) | P2RX3P2RX2MAP3K5 | |
| SCHEMBL10244501 | 0.88 | P2RX3 (0.54) | P2RX3P2RX2WDR5 | |
| SCHEMBL18166289 | 0.88 | P2RX3 (0.39) | P2RX3P2RX2 | |
| SCHEMBL18166416 | 0.87 | P2RX3 (0.40) | P2RX3P2RX2FAAHGRM2CTSA | |
| SCHEMBL18166390 | 0.87 | P2RX3 (0.50) | P2RX3P2RX2FAAH | |
| SCHEMBL18166287 | 0.86 | P2RX3 (0.47) | P2RX3P2RX2FAAH | |
| SCHEMBL18166446 | 0.84 | P2RX3 (0.45) | P2RX3P2RX2 | |
| SCHEMBL18036328 | 0.81 | CNR2 (0.35) | P2RX3P2RX2FAAHGRM2 | |
| SCHEMBL18036437 | 0.81 | CNR2 (0.35) | P2RX3P2RX2FAAHGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |