Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166435 | 0.91 | P2RX3 (0.48) | P2RX3P2RX2TRPV1SMN1; SMN2MAPT | |
| SCHEMBL18166323 | 0.90 | P2RX3 (0.47) | P2RX3P2RX2TRPV1SMN1; SMN2MAPT | |
| SCHEMBL18166351 | 0.89 | P2RX3 (0.46) | P2RX3P2RX2TRPV1SMN1; SMN2MAPT | |
| SCHEMBL18166399 | 0.88 | P2RX3 (0.46) | P2RX3P2RX2TRPV1SMN1; SMN2MAPT | |
| SCHEMBL10243747 | 0.87 | P2RX3 (0.57) | P2RX3P2RX2MAPTLMNAKDM4E | |
| SCHEMBL18166332 | 0.85 | EPHX1 (0.52) | P2RX3P2RX2MAPTEPHX1LMNA | |
| SCHEMBL18166392 | 0.85 | P2RX3 (0.50) | P2RX3P2RX2SMN1; SMN2MAPTEPHX1 | |
| SCHEMBL18166436 | 0.84 | P2RX3 (0.53) | P2RX3P2RX2TRPV1MAPTLMNA | |
| SCHEMBL18166311 | 0.83 | P2RX3 (0.49) | P2RX3P2RX2MAPTLMNA | |
| SCHEMBL18166272 | 0.83 | P2RX3 (0.47) | P2RX3P2RX2SMN1; SMN2MAPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |