Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 12/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166446 | 0.93 | P2RX3 (0.45) | P2RX3P2RX2 | |
| SCHEMBL18166281 | 0.89 | P2RX3 (0.41) | P2RX3P2RX2MAP3K5 | |
| SCHEMBL18166371 | 0.88 | P2RX3 (0.46) | P2RX3P2RX2 | |
| SCHEMBL18166289 | 0.87 | P2RX3 (0.39) | P2RX3P2RX2 | |
| SCHEMBL10245028 | 0.87 | P2RX3 (0.53) | P2RX3P2RX2 | |
| SCHEMBL18166356 | 0.86 | P2RX3 (0.43) | P2RX3P2RX2 | |
| SCHEMBL18166462 | 0.86 | P2RX3 (0.38) | P2RX3P2RX2MEN1LMNACYP1A2 | |
| SCHEMBL18166350 | 0.86 | P2RX3 (0.43) | P2RX3P2RX2 | |
| SCHEMBL18166429 | 0.86 | P2RX3 (0.43) | P2RX3P2RX2 | |
| SCHEMBL18166294 | 0.85 | P2RX3 (0.43) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |