Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18167157 | 0.90 | PIK3CG (0.46) | PIK3CGMAPTSHMT2KDM4EGAA | |
| SCHEMBL18167163 | 0.88 | PIK3CG (0.44) | PIK3CGMAPTBRD4 | |
| SCHEMBL18167162 | 0.87 | PIK3CG (0.44) | PIK3CGMAPTBRD4 | |
| SCHEMBL18167152 | 0.87 | NPC1 (0.37) | PIK3CGMAPTSHMT2KDM4EPIK3CD | |
| SCHEMBL15192968 | 0.86 | PIK3CG (0.42) | PIK3CGMAPTSHMT2KDM4EGAA | |
| SCHEMBL15193666 | 0.86 | MAPT (0.39) | PIK3CGMAPTSHMT2KDM4EGAA | |
| SCHEMBL18167149 | 0.85 | PIK3CG (0.38) | PIK3CGMAPTSHMT2KDM4EGAA | |
| SCHEMBL18167159 | 0.85 | PIK3CG (0.46) | PIK3CGMAPT | |
| SCHEMBL15192985 | 0.85 | MAPT (0.46) | PIK3CGMAPTSHMT2KDM4EGAA | |
| SCHEMBL18167147 | 0.85 | PIK3CG (0.39) | PIK3CGMAPTSHMT2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630129-B1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | claimed |