⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728246 | 0.70 | — | — | |
| SCHEMBL7132808 | 0.68 | TERT (0.38) | — | |
| SCHEMBL2225149 | 0.67 | — | — | |
| SCHEMBL6538151 | 0.65 | — | — | |
| SCHEMBL641601 | 0.63 | TSHR (0.32) | — | |
| SCHEMBL10371841 | 0.63 | — | — | |
| SCHEMBL11315839 | 0.62 | — | — | |
| SCHEMBL431934 | 0.61 | — | — | |
| SCHEMBL4059820 | 0.60 | — | — | |
| SCHEMBL4062497 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2017-12-21 | — | — | US | disclosed |
| WO-2016174551-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2016-11-03 | — | — | WO | disclosed |
| US-20160311805-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2016-10-27 | — | — | US | disclosed |