⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431934 | 0.94 | — | — | |
| SCHEMBL4059820 | 0.91 | — | — | |
| SCHEMBL4062497 | 0.91 | — | — | |
| SCHEMBL1238338 | 0.91 | — | — | |
| SCHEMBL10371841 | 0.77 | — | — | |
| SCHEMBL9800820 | 0.75 | — | — | |
| SCHEMBL6538151 | 0.73 | — | — | |
| SCHEMBL4728246 | 0.73 | — | — | |
| SCHEMBL7338845 | 0.68 | CA2 (0.43) | — | |
| SCHEMBL18170327 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190786-B1 | AZETIDINE DERIVATIVES; PROCESS FOR THEIR PREPARATION; AND THEIR USE AS INTERMEDIATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-04-04 | — | — | EP | claimed |
| EP-3814331-A1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | Phenex-FXR GmbH (DE) | 2021-05-05 | — | — | EP | disclosed |
| EP-2523664-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2012-11-21 | — | — | EP | disclosed |
| US-8232389-B2 | Method for crystallization of azetidinonecarboxylic acid | KANEKA CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8232389-B2 | Method for crystallization of azetidinonecarboxylic acid | KANEKA CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| CN-101479281-B | Improved method for crystallization of azetidinonecarboxylic acid | KANEKA CORP | 2012-07-11 | — | — | CN | disclosed |
| WO-2011088192-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |
| US-20100298556-A1 | Method for crystallization of azetidinonecarboxylic acid | KANEKA CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298556-A1 | Method for crystallization of azetidinonecarboxylic acid | KANEKA CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| CN-101479281-A | Improved method for crystallization of azetidinonecarboxylic acid | KANEGAFUCHI CHEMICAL IND (JP) | 2009-07-08 | — | — | CN | disclosed |
| EP-1187809-A1 | PROCESS FOR REDUCTION OF (2R)-4-OXOAZETIDINONE-2-CARBOXYLIC ACID | ABBOTT LABORATORIES (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000076964-A1 | PROCESS FOR REDUCTION OF (2R)-4-OXOAZETIDINONE-2-CARBOXYLIC ACID | ABBOTT LABORATORIES (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6103911-A | Process for reduction of (2R)-4-oxoazetidinone-2-carboxylic acid | ABBOTT LABORATORIES (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0944594-A4 | INHIBITORS OF THE ENZYMATIC ACTIVITY OF PSA | LILLY CO ELI (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0944594-A1 | INHIBITORS OF THE ENZYMATIC ACTIVITY OF PSA | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0559533-B1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| WO-1998025895-A1 | INHIBITORS OF THE ENZYMATIC ACTIVITY OF PSA | ELI LILLY AND COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |
| US-5589592-A | Process for preparing β-lactam derivative and synthetic intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5414081-A | Treating a 1-aza-3-thiabicycloalkane with base and phosphine or phosphite desulfurizing agent, and reacting the product with an active esterifying agent | TANABE SEIYAKU CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0559533-A1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-08 | — | — | EP | disclosed |