Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.76 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.76 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.76 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420550 | 0.89 | PDK1 (0.76) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL2072672 | 0.88 | MAPT (0.60) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL18784583 | 0.86 | PDK1 (0.57) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL4969610 | 0.85 | PDK1 (0.76) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL2090148 | 0.84 | ALDH1A1 (0.69) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL7299760 | 0.84 | MEN1 (0.59) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL3251744 | 0.82 | KMT2A (0.62) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL8553107 | 0.81 | GRIK1 (0.60) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL1819382 | 0.81 | PDK1 (0.55) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL30641927 | 0.80 | KMT2A (0.66) | PDK1PDK2PDK3PDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461134-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2011060196-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | PDK1 4272/4885PDK2 4242/4885PDK3 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.