⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457473 | 0.88 | THRB (0.32) | — | |
| SCHEMBL192524 | 0.79 | GRIN2D (0.44) | — | |
| Phosphine SCHEMBL28211022 | 0.76 | GRIN2D (0.42) | — | |
| SCHEMBL5269244 | 0.73 | THRB (0.48) | — | |
| SCHEMBL810646 | 0.72 | GRIN1 (0.54) | — | |
| SCHEMBL5269865 | 0.72 | GRIN1 (0.48) | — | |
| SCHEMBL20705522 | 0.69 | — | — | |
| SCHEMBL13506929 | 0.67 | — | — | |
| SCHEMBL11788745 | 0.63 | — | — | |
| SCHEMBL1820632 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077835-A1 | METHOD FOR PREPARING MONOSUBSTITUTED BICYCLO[1.1.1] PENTANE DERIVATIVE | 牛津大学(苏州)科技有限公司 | 2025-04-17 | — | — | WO | disclosed |
| CN-119822937-A | Process for the preparation of mono-substituted bicyclo [1.1.1] pentane derivatives | 牛津大学(苏州)科技有限公司 | 2025-04-15 | — | — | CN | disclosed |
| US-10189780-B2 | Bicyclic alkyl compounds and synthesis | Zeno Royalties & Milestones, LLC (US) | 2019-01-29 | — | — | US | disclosed |
| US-20160311766-A1 | BICYCLIC ALKYL COMPOUNDS AND SYNTHESIS | RECURIUM IP HOLDINGS, LLC | 2016-10-27 | — | — | US | disclosed |