Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269865 | 0.95 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL812216 | 0.83 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL26079847 | 0.83 | GRIN1 (0.39) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Ammonia Solution, Strong SCHEMBL14695768 | 0.80 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL17001201 | 0.77 | THRB (0.46) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL10457473 | 0.76 | THRB (0.32) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL18171379 | 0.72 | — | — | |
| SCHEMBL2763210 | 0.72 | GRIN1 (0.56) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL1072142 | 0.72 | GRIN1 (0.71) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL8061377 | 0.72 | GRIN1 (0.71) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119936252-A | Memantine hydrochloride and detection method of related substances thereof | 宁夏医科大学 | 2025-05-06 | — | — | CN | claimed |
| CN-116947644-B | Preparation method of memantine hydrochloride | 山东轩鸿生物医药有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-116947644-A | Preparation method of memantine hydrochloride | 山东轩鸿生物医药有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-113387815-A | Green preparation method of memantine | 刘振洋 | 2021-09-14 | — | — | CN | claimed |
| CN-102942490-A | Synthesis of memantine hydrochloride | SHAANXI ARK PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | claimed |
| CN-102432473-A | Synthetic method of memantine hydrochloride | GUANGZHOU BOJI PHARMACEUTICAL BIO TECHNOLOGY CO LTD | 2012-05-02 | — | — | CN | claimed |
| CN-1193981-C | Method for preparing memantine hydrochloride | JIANGSU PROV ATOMIC MEDICAL IN (CN) | 2005-03-23 | — | — | CN | claimed |
| CN-1488622-A | Method for preparing memantine hydrochloride | 江苏省原子医学研究所 | 2004-04-14 | — | — | CN | claimed |
| CN-119936252-A | Memantine hydrochloride and detection method of related substances thereof | 宁夏医科大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119936252-A | Memantine hydrochloride and detection method of related substances thereof | 宁夏医科大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-116947644-B | Preparation method of memantine hydrochloride | 山东轩鸿生物医药有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-116947644-A | Preparation method of memantine hydrochloride | 山东轩鸿生物医药有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-113387815-A | Green preparation method of memantine | 刘振洋 | 2021-09-14 | — | — | CN | disclosed |
| CN-113387815-A | Green preparation method of memantine | 刘振洋 | 2021-09-14 | — | — | CN | disclosed |
| WO-2006017188-A2 | MEMANTINE AS ADJUNCTIVE TREATMENT TO ATYPICAL ANTIPSYCHOTICS IN SCHIZOPHRENIA PATIENTS | FOREST LABORATORIES, INC. (US) | 2006-02-16 | — | — | WO | disclosed |
| CN-1193981-C | Method for preparing memantine hydrochloride | JIANGSU PROV ATOMIC MEDICAL IN (CN) | 2005-03-23 | — | — | CN | disclosed |
| CN-1193981-C | Method for preparing memantine hydrochloride | JIANGSU PROV ATOMIC MEDICAL IN (CN) | 2005-03-23 | — | — | CN | disclosed |
| WO-2005002634-A1 | VAPOUR DISPERSION | GIVAUDAN SA (CH) | 2005-01-13 | — | — | WO | disclosed |
| CN-1488622-A | Method for preparing memantine hydrochloride | 江苏省原子医学研究所 | 2004-04-14 | — | — | CN | disclosed |
| US-4122193-A | 1-AMINO-3,5-DIMETHYL-ADAMANTANE, ANTI-HYPERKINESIS | MERZ & CO. (DE) | 1978-10-24 | — | — | US | disclosed |