Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16791914 | 1.00 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL18171383 | 0.84 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL16791898 | 0.84 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL10401106 | 0.73 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL9464386 | 0.73 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL9517517 | 0.73 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL17065127 | 0.72 | KMT2A (0.41) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL10401418 | 0.71 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL10401417 | 0.71 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL17257651 | 0.70 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189780-B2 | Bicyclic alkyl compounds and synthesis | Zeno Royalties & Milestones, LLC (US) | 2019-01-29 | — | — | US | disclosed |
| US-20160311766-A1 | BICYCLIC ALKYL COMPOUNDS AND SYNTHESIS | RECURIUM IP HOLDINGS, LLC | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311766-A1 | BICYCLIC ALKYL COMPOUNDS AND SYNTHESIS | AP1M1, CYP1B1, CYP2C9 | NPC1 311/4885RAB9A 123/4885SMN1; SMN2 2977/4885 |
| US-10189780-B2 | Bicyclic alkyl compounds and synthesis | AP1M1, CYP1B1, CYP2C9 | NPC1 311/4885RAB9A 123/4885SMN1; SMN2 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.