SCHEMBL18171852

SCHEMBL18171852

C=C(CC=CC(=O)O)C(=O)OCCOCCCC

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.44
THRB P10828 1/20 0.38
ATM Q13315 1/20 0.38
TSHR P16473 6/20 0.37
HPGD P15428 1/20 0.36
RARB P10826 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313840 0.91 HCAR2 (0.53) HCAR2ATMTSHRHPGDALDH1A1
Methacrylic Acid SCHEMBL10348380 0.90 TSHR (0.48) HCAR2THRBTSHR
SCHEMBL7617323 0.88 THRB (0.39) HCAR2THRBATMTSHR
SCHEMBL7739132 0.87 TSHR (0.54) HCAR2THRBATMTSHRHPGD
SCHEMBL325215 0.87 HCAR2 (0.54) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL10347496 0.85 HCAR2 (0.55) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL6060612 0.85 HCAR2 (0.55) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL9299634 0.85 HCAR2 (0.55) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL121143 0.85 HCAR2 (0.55) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL10347220 0.85 HCAR2 (0.50) HCAR2THRBATMTSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11578205-B2 Antimicrobial, non-thrombogenic polymer composition LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-02-14 US disclosed
EP-3361868-B1 BIOCIDALLY ACTIVE POLYMER COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2021-12-15 EP disclosed
US-20210277231-A1 Antimicrobial, Non-Thrombogenic Polymer Composition LUBRIZOL ADVANCED MAT INC (US) 2021-09-09 US disclosed
US-10829606-B2 Surface modified polymer compositions LUBRIZOL ADVANCED MATERIALS, INC. 2020-11-10 US disclosed
US-10827757-B2 Biocidally active polymer compositions LUBRIZOL ADVANCED MATERIALS, INC. 2020-11-10 US disclosed
EP-3285818-B1 SURFACE MODIFIED POLYMER COMPOSITIONS LUBRIZOL ADVANCED MATERIALS INC (US) 2020-09-23 EP disclosed
US-20190191703-A1 BIOCIDALLY ACTIVE POLYMER COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. 2019-06-27 US disclosed
EP-3361868-A1 BIOCIDALLY ACTIVE POLYMER COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2018-08-22 EP disclosed
WO-2018140911-A1 ANTIMICROBIAL, NON-THROMBOGENIC POLYMER COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2018-08-02 WO disclosed
US-20180105665-A1 SURFACE MODIFIED POLYMER COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. 2018-04-19 US disclosed
EP-3285818-A1 SURFACE MODIFIED POLYMER COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2018-02-28 EP disclosed
WO-2017066242-A1 BIOCIDALLY ACTIVE POLYMER COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-04-20 WO disclosed
WO-2016172460-A1 SURFACE MODIFIED POLYMER COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190191703-A1 BIOCIDALLY ACTIVE POLYMER COMPOSITIONS PUF60, FGB, PARG HCAR2 4424/4885THRB 3659/4885ATM 3347/4885
US-10827757-B2 Biocidally active polymer compositions PUF60, FGB, PARG HCAR2 4424/4885THRB 3659/4885ATM 3347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.