Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 18/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18171870 | 0.99 | RPS6KB1 (0.59) | RPS6KB1IDO1TDO2CCNT1CDK9 | |
| SCHEMBL18176557 | 0.90 | RPS6KB1 (0.59) | RPS6KB1CCNT1CDK9 | |
| SCHEMBL18176549 | 0.88 | RPS6KB1 (0.72) | RPS6KB1 | |
| SCHEMBL18176403 | 0.88 | RPS6KB1 (0.72) | RPS6KB1 | |
| SCHEMBL18176402 | 0.79 | RPS6KB1 (0.69) | RPS6KB1 | |
| SCHEMBL18176281 | 0.79 | RPS6KB1 (0.69) | RPS6KB1 | |
| SCHEMBL18176554 | 0.78 | RPS6KB1 (0.58) | RPS6KB1 | |
| SCHEMBL18176579 | 0.77 | RPS6KB1 (0.73) | RPS6KB1 | |
| SCHEMBL18176574 | 0.77 | RPS6KB1 (0.72) | RPS6KB1 | |
| SCHEMBL18171868 | 0.76 | MAPK1 (0.37) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |