Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PTPRC | P08575 | 5/20 | 0.63 |
| ▸ | PTPRG | P23470 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28492309 | 0.82 | KMT2A (0.53) | KMT2APTPRCPTPRGMAPTABCC1 | |
| SCHEMBL28492310 | 0.81 | KMT2A (0.44) | KMT2APTPRCPTPRGMAPTABCC1 | |
| SCHEMBL18171967 | 0.81 | KMT2A (0.55) | KMT2ALMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7246054 | 0.79 | KMT2A (0.56) | KMT2APTPRCPTPRGMAPTABCC1 | |
| SCHEMBL7820891 | 0.78 | KMT2A (1.00) | KMT2APTPRCPTPRGMAPTLMNA | |
| SCHEMBL9334847 | 0.78 | PTPRC (0.58) | KMT2APTPRCPTPRGMAPTABCC1 | |
| SCHEMBL7824888 | 0.77 | PTPRC (0.58) | KMT2APTPRCPTPRGMAPTABCC1 | |
| SCHEMBL7823071 | 0.77 | KDM4E (0.59) | KMT2APTPRCPTPRGMAPTABCC1 | |
| SCHEMBL28488939 | 0.74 | KMT2A (0.48) | KMT2APTPRCPTPRGMAPTLMNA | |
| SCHEMBL7830138 | 0.74 | PTPRG (1.00) | KMT2APTPRCPTPRGMAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531704-B | Pesticidally active polycyclic derivatives with sulfur-substituted five-membered ring heterocycles | 先正达参股股份有限公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-108040481-B | Pesticidally active polycyclic derivatives with sulfur-substituted five-membered ring heterocycles | 先正达参股股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| EP-3286187-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| EP-3286187-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| US-10125139-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five-membered ring heterocycles | SYNGENTA CROP PROTECTION AG (CH) | 2018-11-13 | — | — | US | disclosed |
| US-10104893-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five membered ring heterocyles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-23 | — | — | US | disclosed |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| EP-3286187-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | Syngenta Participations AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| EP-3286186-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | Syngenta Participations AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| CN-107531704-A | Five-membered ring heterocycle with sulphur substitution kills harmful organism activity Polycyclic derivative | 先正达参股股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2016169882-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016169886-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA CROP PROTECTION AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016169882-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016169886-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA CROP PROTECTION AG (CH) | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | DDT, NIT2, SQOR | KMT2A 1827/4885PTPRC 2325/4885PTPRG 1766/4885 |
| US-10104893-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five membered ring heterocyles | SQOR, DDT, QSOX1 | KMT2A 1556/4885PTPRC 2451/4885PTPRG 2082/4885 |
| US-10125139-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five-membered ring heterocycles | DDT, SQOR, NIT2 | KMT2A 2493/4885PTPRC 2768/4885PTPRG 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.