SCHEMBL18172

SCHEMBL18172

c1ccc2c(c1)CCCN2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
TSHR P16473 1/20 0.48
KDM4E B2RXH2 3/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
ALOX15 P16050 2/20 0.45
HSD17B10 Q99714 2/20 0.45
NPC1 O15118 1/20 0.43
MAPK13 O15264 1/20 0.43
MAPK12 P53778 1/20 0.43
MAPK11 Q15759 1/20 0.43
MAPK14 Q16539 1/20 0.43
GAA P10253 2/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
THRB P10828 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27392334 1.00 MAPT (0.50) MAPTTSHRKDM4ECA12CA1
SCHEMBL29370549 1.00 MAPT (0.50) MAPTTSHRKDM4ECA12CA1
Phosphine SCHEMBL241499 0.98 MAPT (0.48) MAPTTSHRKDM4ECA12CA1
Hydrochloric Acid SCHEMBL30018404 0.98 MAPT (0.48) MAPTTSHRKDM4ECA12CA1
Benzene SCHEMBL29053622 0.98 MAPT (0.50) MAPTTSHRKDM4ECA12CA1
SCHEMBL517747 0.98 MAPT (0.48) MAPTTSHRKDM4ECA12CA1
Methane SCHEMBL11211553 0.98 MAPT (0.48) MAPTTSHRKDM4ECA12CA1
SCHEMBL7259924 0.98 MAPT (0.48) MAPTTSHRKDM4ECA12CA1
Hydrochloric Acid SCHEMBL5370795 0.98 MAPT (0.48) MAPTTSHRKDM4ECA12CA1
SCHEMBL8215775 0.98 MAPT (0.48) MAPTTSHRKDM4ECA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 46489 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS DONG-A ST CO., LTD. (KR) 2026-05-28 US claimed
CN-122079987-A Method for synthesizing tetrahydroquinoline compound by using pinacol biborate as reducing agent 2026-05-26 CN claimed
WO-2026103601-A1 RU-NI BIMETALLIC CATALYST FOR SELECTIVE HYDROGENATION OF QUINOLINE ORGANIC HYDROGEN STORAGE CARRIER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 天府永兴实验室 2026-05-21 WO claimed
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US claimed
CN-118005569-B 6-Aminoquinoxaline compound and preparation method and application thereof 华南理工大学 2026-05-19 CN claimed
CN-122059875-A Method for synthesizing quinoline compound by catalytic dehydrogenation of tetrahydroquinoline compound 西安石油大学 2026-05-19 CN claimed
EP-4727947-A1 DYNAMIC COVALENT CHEMISTRY OF SPIROPYRANS FOR SYNTHESIS OF PHOTOSWITCHABLE PHOTOINITIATORS AND USES THEREOF Xolo GmbH (DE) 2026-04-22 EP claimed
US-20260102962-A1 Dynamic Covalent Chemistry of Spiropyrans for Synthesis of Photoswitchable Photoinitiators and Uses Thereof, and Process for Locally Polymerizing a Starting Material by Dual Color Photopolymerization XOLO GMBH (DE) 2026-04-16 US claimed
US-20260097029-A1 Tetrahydroquinoline Compounds As Antitumor Agents COSCONATI SANDRO (IT) 2026-04-09 US claimed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP claimed
US-4104380-A Dibenzyl glycolic acid derivatives WARNER-LAMBERT COMPANY (US) 1978-08-01 US claimed
US-4055427-A Process of hardening a silver halide photographic material with a 1-carbamoyloxypyridinium salt AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1977-10-25 US claimed
US-4055542-A PEROXIDE THREE BOND CO., LTD. (JA) 1977-10-25 US claimed
US-4036979-A ANIMAL GROWTH RATE ACCELERATOR AMERICAN CYANAMID COMPANY (US) 1977-07-19 US claimed
US-4025090-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1977-05-24 US claimed
US-3992386-A 4(Quinolyl)phenoxy alkanoic acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-11-16 US claimed
US-3984246-A MONO-, TRI-, OR PENTAMETHINE OXONOLES OF 1-SULFOLANYL PYRAZOLONES AGFA-GEVAERT, A.G. (DT) 1976-10-05 US claimed
US-3976651-A BACTERICIDE RIKER LABORATORIES, INC. (US) 1976-08-24 US claimed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US claimed
US-3933748-A Anaerobic adhesive containing tetrahydroquinoline and benzosulfimide OKURA KOGYA KABUSHIKI KAISHA (JA) 1976-01-20 US claimed