Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL18173563 | 0.99 | AOC3 (0.59) | AOC3RAB9A | |
| SCHEMBL18173571 | 0.96 | AOC3 (0.59) | AOC3RAB9A | |
| SCHEMBL12094922 | 0.95 | AOC3 (0.65) | AOC3RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL1973686 | 0.95 | AOC3 (0.65) | AOC3RAB9AKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL18173566 | 0.94 | AOC3 (0.64) | AOC3RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL18953107 | 0.82 | AOC3 (0.62) | AOC3ALDH1A1 | |
| SCHEMBL11516578 | 0.81 | AOC3 (0.58) | AOC3RAB9ASMN1; SMN2 | |
| Sulfuric Acid SCHEMBL28571413 | 0.78 | AOC3 (0.67) | AOC3 | |
| Sulfuric Acid SCHEMBL28571415 | 0.78 | AOC3 (0.67) | AOC3 | |
| SCHEMBL1976869 | 0.78 | AOC3 (0.64) | AOC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286190-B1 | PHARMACEUTICAL SALT FORMS OF AN INHIBITOR OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) | BENEVOLENTAI CAMBRIDGE LTD (GB) | 2020-06-03 | — | — | EP | claimed |
| EP-3286190-A1 | PHARMACEUTICAL SALT FORMS OF AN INHIBITOR OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) | Proximagen Limited (GB) | 2018-02-28 | — | — | EP | claimed |
| WO-2016170351-A1 | PHARMACEUTICAL SALT FORMS OF AN INHIBITOR OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) | PROXIMAGEN LIMITED (GB) | 2016-10-27 | — | — | WO | claimed |
| EP-3286190-B1 | PHARMACEUTICAL SALT FORMS OF AN INHIBITOR OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) | BENEVOLENTAI CAMBRIDGE LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| EP-3386494-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | Benevolentai Cambridge Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| EP-3286190-A1 | PHARMACEUTICAL SALT FORMS OF AN INHIBITOR OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) | Proximagen Limited (GB) | 2018-02-28 | — | — | EP | disclosed |
| EP-3285767-A1 | TREATMENT OF PAIN | Proximagen Limited (GB) | 2018-02-28 | — | — | EP | disclosed |
| WO-2017098236-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | PROXIMAGEN LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |
| WO-2016170353-A1 | TREATMENT OF PAIN | PROXIMAGEN LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016170351-A1 | PHARMACEUTICAL SALT FORMS OF AN INHIBITOR OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) | PROXIMAGEN LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |