SCHEMBL18174553

SCHEMBL18174553

Cc1cc(-c2c3ccccc3c(-c3ccc(-c4ccncc4)c(C)c3)c3ccccc23)ccc1-c1ccncc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 4/20 0.44
IMPDH2 P12268 3/20 0.42
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ESR2 Q92731 1/20 0.41
MAPK14 Q16539 2/20 0.40
PIK3CA P42336 1/20 0.40
SLC2A1 P11166 1/20 0.39
PDE3B Q13370 2/20 0.39
PDE3A Q14432 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174626 0.91 GRM4 (0.42) LRRK2IMPDH2MAPK1HSD17B10MEN1
SCHEMBL18174621 0.91 MEN1 (0.48) LRRK2IMPDH2MAPK1HSD17B10MEN1
SCHEMBL18174665 0.90 DHODH (0.47) LRRK2IMPDH2MAPK14SLC2A1CYP17A1
SCHEMBL15160985 0.90 PIK3CA (0.49) LRRK2IMPDH2MEN1KMT2AKDM4E
SCHEMBL18174603 0.87 PIK3CA (0.47) LRRK2IMPDH2MEN1KMT2AKDM4E
SCHEMBL18174639 0.87 PIK3CA (0.44) LRRK2IMPDH2PIK3CA
SCHEMBL18174604 0.87 PIK3CA (0.47) LRRK2IMPDH2MEN1KMT2AKDM4E
SCHEMBL18174712 0.87 DHODH (0.44) LRRK2IMPDH2MAPTMAPK14PIK3CA
SCHEMBL18174705 0.86 CYP2A6 (0.38) LRRK2IMPDH2MEN1KMT2AKDM4E
SCHEMBL18174585 0.86 MAPK9 (0.44) LRRK2MAPK1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed