SCHEMBL18174585

SCHEMBL18174585

Cc1cc(-c2c3ccccc3c(-c3ccc(-c4ccncc4)c(C)c3)c3cc(-c4ccc5ccccc5c4)ccc23)ccc1-c1ccncc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 5/20 0.44
MAPK10 P53779 5/20 0.44
MAPK8 P45983 3/20 0.44
MAPK14 Q16539 7/20 0.43
CSNK1D P48730 6/20 0.43
MAPK11 Q15759 6/20 0.43
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
CHEK1 O14757 1/20 0.37
IKBKB O14920 1/20 0.37
PIK3CA P42336 1/20 0.37
LRRK2 Q5S007 1/20 0.37
MAPT P10636 2/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174596 0.91 MAPK9 (0.43) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL10032215 0.90 MAPK9 (0.43) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL15160985 0.88 PIK3CA (0.49) CYP17A1CHEK1PIK3CALRRK2MAPT
SCHEMBL18174601 0.86 CYP11B1 (0.56) CYP17A1CYP19A1CYP11B1CYP11B2MAPT
SCHEMBL15077951 0.86 MAPK9 (0.50) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL15977682 0.86 MAPK9 (0.50) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL18174553 0.86 LRRK2 (0.44) MAPK14MAPK11CYP17A1PIK3CALRRK2
SCHEMBL15977889 0.86 CYP11B1 (0.44) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL18174603 0.86 PIK3CA (0.47) CYP17A1CHEK1IKBKBPIK3CALRRK2
SCHEMBL18174604 0.86 PIK3CA (0.47) CYP17A1CHEK1PIK3CALRRK2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed