SCHEMBL18174705

SCHEMBL18174705

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5)c(C)c4)c4ccccc34)cc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.38
LRRK2 Q5S007 3/20 0.37
SLC2A1 P11166 1/20 0.37
IMPDH2 P12268 2/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAPK14 Q16539 1/20 0.36
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
FYN P06241 1/20 0.35
PIK3CA P42336 1/20 0.35
KDR P35968 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174672 0.92 CYP2A6 (0.38) CYP2A6LRRK2SLC2A1IMPDH2MEN1
SCHEMBL18174777 0.90 CYP2A6 (0.40) CYP2A6IMPDH2MEN1KMT2AKDM4E
SCHEMBL18174747 0.89 CYP2A6 (0.46) CYP2A6IMPDH2MEN1KMT2AKDM4E
SCHEMBL15160973 0.89 SLC2A1 (0.46) CYP2A6SLC2A1KDM4ELMNAMAPT
SCHEMBL18174627 0.87 GRM4 (0.40) CYP2A6S1PR1S1PR3PIK3CACYP11B1
SCHEMBL18174553 0.86 LRRK2 (0.44) LRRK2SLC2A1IMPDH2MEN1KMT2A
SCHEMBL15160987 0.85 CYP2A6 (0.41) CYP2A6LRRK2IMPDH2PIK3CACYP11B1
SCHEMBL15160916 0.84 DHODH (0.46) CYP2A6CYP11B1CYP11B2CYP17A1CYP1A2
SCHEMBL18174702 0.84 RAF1 (0.36) CYP2A6KDM4EKDRCYP17A1NPC1
SCHEMBL18174626 0.84 GRM4 (0.42) LRRK2SLC2A1IMPDH2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed