SCHEMBL18174561

SCHEMBL18174561

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc(C)cn5)cc4)c4ccccc34)cc2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.54
CCR5 P51681 1/20 0.54
CCR8 P51685 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
CYP3A4 P08684 2/20 0.51
CYP2A6 P11509 1/20 0.51
KDM1A O60341 1/20 0.41
METAP2 P50579 1/20 0.41
ACHE P22303 1/20 0.40
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
PIM1 P11309 2/20 0.37
P2RX7 Q99572 1/20 0.37
AURKA O14965 1/20 0.37
ABL1 P00519 1/20 0.37
NTRK1 P04629 1/20 0.37
LCK P06239 1/20 0.37
CSF1R P07333 1/20 0.37
RET P07949 1/20 0.37
MET P08581 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161016 0.88 CYP3A4 (0.45) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL15977627 0.88 CYP3A4 (0.45) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL18174644 0.88 CYP3A4 (0.45) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10300893 0.87 CYP3A4 (0.47) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL15160974 0.87 CYP2A6 (0.48) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL17589446 0.86 CCR1 (0.65) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032679 0.85 CYP3A4 (0.43) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL18174600 0.85 CYP3A4 (0.43) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL18174692 0.85 DYRK1A (0.43) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10032730 0.85 CYP3A4 (0.45) CCR1CCR5CCR8HDAC6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed