SCHEMBL18174692

SCHEMBL18174692

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccnc(C)c5)cc4)c4ccccc34)cc2)nc1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2A6 P11509 1/20 0.43
WNT3A P56704 14/20 0.42
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
PDK2 Q15119 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174734 0.92 CYP3A4 (0.43) DYRK1ACYP3A4CYP2A6WNT3A
SCHEMBL18174561 0.85 CCR1 (0.54) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL16189065 0.85 DYRK1A (0.56) DYRK1ACYP3A4WNT3APDK2
SCHEMBL18174644 0.83 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174655 0.83 DYRK1A (0.45) DYRK1ACYP2A6WNT3ACCR1CCR5
SCHEMBL15977627 0.83 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL15161016 0.83 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174699 0.82 CYP3A4 (0.46) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL10032679 0.81 CYP3A4 (0.43) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174600 0.81 CYP3A4 (0.43) CYP3A4CYP2A6CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed