SCHEMBL18174600

SCHEMBL18174600

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc(C)cn5)cc4)c4cc(-c5cccc(-c6ccccc6)c5)ccc34)cc2)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
CYP2A6 P11509 1/20 0.43
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
PSMB5 P28074 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
FLT3 P36888 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977627 0.97 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL15161016 0.97 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174644 0.97 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174581 0.95 CYP3A4 (0.43) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL10300893 0.92 CYP3A4 (0.47) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL10032679 0.86 CYP3A4 (0.43) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL15977479 0.86 HSD17B1 (0.46) CYP11B1CYP11B2PSMB5HSD17B1HSD17B2
SCHEMBL15977436 0.86 HSD17B1 (0.46) CYP11B1CYP11B2PSMB5HSD17B1HSD17B2
SCHEMBL18174561 0.85 CCR1 (0.54) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL10032924 0.85 CYP3A4 (0.42) CYP3A4CYP2A6CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed