Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15161039 | 0.95 | GRM4 (0.46) | GRM4CYP17A1CYP1A2CYP19A1DHODH | |
| SCHEMBL18174625 | 0.94 | DHODH (0.48) | GRM4CYP17A1CYP1A2DHODHRPS6KA3 | |
| SCHEMBL18174776 | 0.92 | GRM4 (0.43) | GRM4CYP17A1CYP1A2CYP19A1DHODH | |
| SCHEMBL18174758 | 0.91 | GRM4 (0.43) | GRM4CYP17A1CYP1A2CYP19A1DHODH | |
| SCHEMBL18174750 | 0.91 | GRM4 (0.43) | GRM4CYP17A1CYP1A2CYP19A1DHODH | |
| SCHEMBL9612937 | 0.89 | TNF (0.49) | GRM4CYP17A1CYP1A2CYP19A1DHODH | |
| SCHEMBL18174626 | 0.89 | GRM4 (0.42) | GRM4CYP17A1CYP1A2CYP19A1DHODH | |
| SCHEMBL18174759 | 0.88 | CYP17A1 (0.46) | GRM4CYP17A1CYP1A2DHODHS1PR1 | |
| SCHEMBL9612933 | 0.88 | TNF (0.48) | GRM4CYP17A1CYP1A2CYP19A1DHODH | |
| SCHEMBL18174551 | 0.88 | PIK3CA (0.46) | GRM4CYP17A1CYP1A2CYP19A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| US-20150203469-A1 | ISOTOPOLOGUES OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL) PIPERIDINE-2-6-DIONE AND METHODS OF PREPARATION THEREOF | CELGENE CORPORATION | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203469-A1 | ISOTOPOLOGUES OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL) PIPERIDINE-2-6-DIONE AND METHODS OF PREPARATION THEREOF | AQP3, CYP2D6, CYP3A5 | GRM4 3178/4885CYP17A1 1790/4885CYP1A2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.