SCHEMBL18174567

SCHEMBL18174567

Cc1cccnc1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4ncccc4C)cc3)c3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.53
TRPV1 Q8NER1 9/20 0.46
CNR2 P34972 1/20 0.44
METAP2 P50579 1/20 0.41
PDK1 Q15118 2/20 0.40
DHODH Q02127 1/20 0.40
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
NPC1 O15118 1/20 0.39
HSP90AA1 P07900 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SYK P43405 1/20 0.39
AURKB Q96GD4 1/20 0.39
INCENP Q9NQS7 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174697 0.89 CYP2A6 (0.47) CYP2A6TRPV1CNR2METAP2PDK1
SCHEMBL18174709 0.89 MKNK1 (0.46) CYP2A6TRPV1CNR2DHODH
SCHEMBL15977631 0.88 CYP2A6 (0.46) CYP2A6TRPV1CNR2PDK1DHODH
SCHEMBL15160986 0.88 CYP2A6 (0.46) CYP2A6TRPV1CNR2PDK1DHODH
SCHEMBL10300898 0.87 CYP2A6 (0.49) CYP2A6TRPV1CNR2METAP2PDK1
SCHEMBL18174654 0.87 DYRK1A (0.44) CYP2A6TRPV1CNR2PDK1
SCHEMBL10032745 0.87 HTR2B (0.45) CYP2A6TRPV1CNR2PDK1DHODH
SCHEMBL18174649 0.85 CYP2A6 (0.51) CYP2A6TRPV1CNR2METAP2PDK1
SCHEMBL18174610 0.85 CYP2A6 (0.44) CYP2A6TRPV1CNR2PDK1DHODH
SCHEMBL18174641 0.85 CYP2A6 (0.44) CYP2A6TRPV1CNR2PDK1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed